Determination of Dissociation Constants of Some Novel Tetrahydropyrimidine Derivatives in Mixed Organic-Water System by Simple pH Measurement
نویسندگان
چکیده
Some tetrahydropyrimidine derivatives have been synthesized and their structures have been confirmed by IR, 1H NMR, 13C NMR and mass spectral data. The dissociation constants of these derivatives of tetrahydropyrimidine have been measured by Calvin Bjerrum pH titration method in DMF-water (60: 40 v/v) system at 303.15 K. It is observed that dissociation constant depends on substituent groups present in the compounds.
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